Main functions

differential_splicing()

Perform pairwise differential splicing analysis.

make_differential_splicing_plot()

Make sashimi-esque plot with ggplot2

Internal functions

dirichlet_multinomial_anova_mc()

Dirichlet multinomial GLM likelihood ratio test for a single cluster

get_intron_meta()

Make a data.frame of meta data about the introns

map_clusters_to_genes()

Work out which gene each cluster belongs to. Note the chromosome names used in the two inputs must match.

leaf_cutter_effect_sizes()

Per intron effect sizes

cluster_results_table()

Parse output of differential_splicing

Helper functions

add_chr()

Adding "chr" if it's not present

beta_real()

Convert K-1 representation of parameters to real

bh()

Benjamini-Hochberg FDR correction

logistic()

logistic (sigmoid) function

multiqq()

Plot multiple qq plot for p-values

Deprecated

dirichlet_multinomial_anova()

Dirichlet multinomial GLM likelihood ratio test for a single cluster (single overdispersion parameter)

dirichlet_multinomial_glm()

Dirichlet multinomial GLM (single overdispersion parameter)

betaBinomialGLM()

Beta binomial GLM likelihood ratio testing