We recommend using dirichlet_multinomial_glm_anova_mc instead.

dirichlet_multinomial_anova(
  xFull,
  xNull,
  y,
  concShape = 1.0001,
  concRate = 1e-04
)

Arguments

xFull

[samples] x [covariates] matrix for the alternative model

xNull

[samples] x [covariates] matrix for the null model

y

[samples] x [introns] matrix of intron usage counts

concShape

Gamma shape parameter for concentration parameter

concRate

Gamma rate parameter for concentration parameter